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Search results for paliperidone root_notes_note in Note (approximate match)
Status:
US Approved Rx
(2015)
Source:
ANDA203802
(2015)
Source URL:
First approved in 2006
Source:
NDA021999
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Paliperidone (9-OH-risperidone) is the primary active metabolite of the older antipsychotic risperidone. While its specific mechanism of action is unknown, it is believed that paliperidone and risperidone act via similar if not the same pathways. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug. Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. Very common adverse effects are: headache, tachycardia, somnolence and insomnia.
Status:
Excipient
Source:
0.09%w/v INFILTRATION INJECTABLE, LIPOSOMAL
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
DIPALMITOYLPHOSPHATIDYLGLYCEROL (DPPG) is a phosphatidylglycerol in which the phosphatidyl acyl groups are both palmitoyl. DPPG is one of the commonly used lipids in liposome studies and biological systems research.
Status:
Possibly Marketed Outside US
Source:
Ascuoli by HEALGROW INC
(2023)
Source URL:
First approved in 2023
Source:
Ascuoli by HEALGROW INC
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)